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The HKU E-learning Platform in Clinical Medicine
The HKU E-learning Platform in Clinical Medicine
  • Physical Examination Skills
    • General Examination
    • Examination of the Cardiovascular System
    • Examination of the Gastrointestinal System
    • Examination of the Neurological System
    • Examination of the Respiratory System
    • Examination of the Musculoskeletal System
    • Demonstration on putting on a surgical/ N95 mask properly
  • eLearning Materials of Individual Divisions
    • Cardiology
    • Clinical Pharmacology
    • Dermatology
    • Endocrinology
    • Gastroenterology & Hepatology
    • Geriatrics
      • Common Physical Signs in the Geriatric Setting
      • Commonly used Assessments in the Geriatric Setting
    • Haematology
    • Infectious Diseases
    • Nephrology
      • General Nephrology
      • Imaging
      • Peritoneal Dialysis
      • Hemodialysis
    • Neurology
    • Rehabilitation Medicine
      • Modified Ashworth Scale
      • Complex Regional Pain Syndrome
      • Case 1
      • Case 2
    • Respiratory Medicine
    • Rheumatology
      • Common Rheumatological Cases
      • Clinical Signs and Radiographs of Patients with Rheumatological Disorders
  • Credits
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Nephrology
General Nephrology

Amyloidosis

July 10th, 2015

Amyloidosis

Courtesy of Dr. KW Chan and Dr. G. Chan, Department of Pathology, Queen Mary Hospital

This is a renal biopsy from a patient with amyloidosis who presented with nephrotic-range proteinuria. The classical histopathological features include nodular glomerular lesions which are Congo Red positive (arrow). These nodular lesions will show apple-green birefringence under polarized light examination. Electron microscopy will reveal wavy amyloid fibrils with diameter ranging 5-25 nm.

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